Sugar Blues
Many years ago I went to a meeting of the Neurootologic and Equilibriometric Society in Turku, Finland. A physician from the upper New York State, Dr. William Updegraff [1], presented a paper about impaired carbohydrate metabolism and idiopathic Menière's disease. I was quite impressed with his insulin tolerance curves, based on the work of Dr. Joseph Kraft [2]. I became interested in this study and began to order glucose and insulin tolerance curves in my patients with a clinical suspicion of carbohydrate metabolic disorders. In a period of one year I collected 100 of these tolerance tests. In 1992 my associate and dear friend Yotaka Fukuda was working on a research project for his Doctorate thesis. He had to abandon the project, however, due to insurmountable difficulties and discussed the problem with me. I offered him my collection of glucose and insulin tolerance curves, suggesting that he could use this material for his doctorate thesis. Yotaka Fukuda, between Jun-